Fernand Labrie

Publications

Page 6 of 9, showing 50 records out of 402 total, starting on record 251, ending on 300

Publication Category Year
152. Sourla, A., Martel, C., Labrie, C., Labrie, F. (1998) Almost exclusive androgenic action of dehydroepiandrosterone in the rat mammary gland. Endocrinology, 139: 753-764. Intracrinology 1998
151. Tremblay, A., Tremblay, G.B., Labrie, C., Labrie, F., Giguère, V. (1998) EM-800, a novel antiestrogen, acts as a pure antagonist of the transcriptional functions of estrogen receptors α and β. Endocrinology, 139: 111-118. Intracrinology 1998
150. Tremblay, G.B., Tremblay, A., Labrie, F., Giguère, V. (1998) Ligand-independent activation of the estrogen receptors α and β by mutations of a conserved tyrosine can be abolished by antiestrogens. Cancer Res., 58: 877-881. Intracrinology 1998
149. Labrie, F. (1998) DHEA as physiological replacement therapy at menopause. J. Endocrinol. Invest., 21: 399-401. Intracrinology 1998
148. Sourla, A., Flamand, M., Bélanger, A., Labrie, F. (1998) Effect of dehydroepiandrosterone on vaginal and uterine histomorphology in the rat. J. Steroid Biochem. Mol. Biol., 66: 137-149. Intracrinology 1998
147. Coquet, A., Boudreau, N., Merand, Y., Labrie, F. (1998) Validated high-performance liquid chromatographic methods for quantitation of a novel nonsteroidal antiestrogen. J. Chromatogr. A, 828: 247-258. Intracrinology 1998
146. Boivin, R.P., Poirier, D., Labrie, F. (1999) 17alpha-alkan (or alkyn) amide derivatives of estradiol as inhibitors of steroid-sulfatase activity. Steroids, 64: 825-833. Intracrinology 1999
145. Labrie, F. (1999) Combined androgen blockade: its unique efficacy for the treatment of localized prostate cancer, in: De Vita, V.T., Hellman, S. et Rosenberg, S.A., eds: Cancer: Principles and Practice of Oncology, Philadelphia, Lippincott-Raven, pp 1-9. Intracrinology 1999
144. Labrie, F. (1999) Prostate cancer: Endocrinology of prostate cancer-intracrinology, in: Pinchera, A., Bertega, X., Binder, C., Fischer, J. et Braverman, L., eds: Textbook of Clinical Endocrinology, Milan, Italy, McGraw-Hill Libri Italia Srl, pp 13-16. Intracrinology 1999
143. Labrie, F., Bélanger, A., Simard, J., Luu-The, V., Labrie, C., Lin, S.-X., Candas, B., Cusan, L. (1999) Impact de l'intracrinologie dans la thérapeutique et la prévention des cancers du sein et de la prostate et de la ménopause, in: Guérité, N. et Leclère, J., eds: Mises au point cliniques d'endocrinologie, nutrition et métabolisme 1999, Paris, France, Les Éditions de Médecine Pratique, pp 169-204. Intracrinology 1999
142. Labrie, F., Candas, B. (1999) Bicalutamide versus Flutamide in combination therapy [Letter to the Editor re: Schellhammer et al. 50: 330-336, 1997]. Urology, 53: 662-663. Intracrinology 1999
141. Labrie, F., Cusan, J., Gomez, J., Levesque, J., Candas, B. (1999) Screening and treatment of localized prostate cancer decreases mortality: first analysis of the first prospective and randomized study on prostate cancer screening. Society of the Study of the Aging Male, 2: 33-43. Intracrinology 1999
140. van der Kwast, T.H., Labrie, F., Têtu, B. (1999) Persistence of high-grade prostatic intra-epithelial neoplasia under combined androgen blockade therapy. Hum. Pathol., 30: 1503-1507. Intracrinology 1999
139. van der Kwast, T.H., Têtu, B., Candas, B., Gomez, J.-L., Cusan, L., Labrie, F. (1999) Prolonged neoadjuvant combined androgen blockade leads to a further reduction of prostatic tumor volume: three versus six months of endocrine therapy. Urology, 53: 523-529. Intracrinology 1999
138. Couillard, S., Gutman, M., Labrie, F., Candas, B., Labrie, C. (1999) Effect of the combined treatment with the pure antiestrogen EM-800 and radiotherapy on the growth of human ZR-75-1 breast cancer xenografts in nude mice. Cancer Res., 59: 4857-4863. Intracrinology 1999
137. Gutman, M., Couillard, S., Labrie, F., Candas, B., Labrie, C. (1999) Effects of the antiestrogen EM-800 (SCH 57050) and cyclophosphamide alone and in combination on growth of human ZR-75-1 breast cancer xenografts in nude mice. Cancer Res., 59: 5176-5180. Intracrinology 1999
136. Hida, N., Poulin, R., Veilleux, R., Labrie, F. (1999) Differential androgen sensitivity is associated with clonal heterogeneity in steroid metabolism, ornithine decarboxylase regulation and IL-1alpha action in mouse mammary tumor cells. J. Steroid Biochem. Mol. Biol., 71: 71-81. Intracrinology 1999
135. Labrie, F., Labrie, C., Bélanger, A., Simard, J., Gauthier, S., Luu-The, V., Mérand, Y., Giguère, V., Candas, B., Luo, S., Martel, C., Singh, S.M., Fournier, M., Coquet, A., Richard, V., Charbonneau, R., Charpenet, G., Tremblay, A., Tremblay, G., Cusan, L., Veilleux, R. (1999) EM-652 (SCH 57068), a third generation SERM acting as pure antiestrogen in the mammary gland and endometrium. J. Steroid Biochem. Mol. Biol., 69: 51-84. Intracrinology 1999
134. Pelletier, G., Luu-The, V., Charbonneau, A., Labrie, F. (1999) Cellular localization of estrogen receptor beta messenger ribonucleic acid in cynomolgus monkey reproductive organs. Biol. Reprod., 61: 1249-1255. Intracrinology 1999
133. Tremblay, G.B., Tremblay, A., Labrie, F., Giguère, V. (1999) Dominant activity of activation function-1 (AF-1) and differential stoichiometric requirements for AF-1 and -2 in the estrogen receptor α⁄β heterodimeric complex. Mol. Cell. Biol., 19: 1919-1927. Intracrinology 1999
132. Labrie, F. (1999) Potential of DHEA as hormone replacement therapy, in Reproductive Medicine: Past Present and Future. Proceeding of the 10th World Congress on Human Reproduction, Salvador, Bahia, Brazil, Parthenon Publishing, pp 224-237. Intracrinology 1999
131. Labrie, F., Bélanger, A., Luu-The, V., Labrie, C., Simard, J., Lin, S.-X. (1999) DHEA, the precursor of androgens and estrogens in peripheral tissues in the human: intracrinology, in: Kalimi, M. et Regelson, W., eds: Dehydroepiandrosterone (DHEA) Biochemical, Physiological and Clinical Aspects, Berlin, New York, Walter de Gruyter, pp 299-342. Intracrinology 1999
130. Labrie, F., Bélanger, A., Luu-The, V., Simard, J., Lin, S.-X., Cusan, L., Labrie, C. (1999) Role of DHEA transformation into androgens and estrogens in peripheral intracrine tissues, in: Thijssen, J.H.H. et Nieuwenhuyse, H., eds: DHEA a comprehensive review (Proceedings Workshop, Amsterdam 1997), New York, Parthenon Publishing, pp 69-103. Intracrinology 1999
129. Tchernof, A., Labrie, F., Després, J.P. (1999) DHEA, obesity and cardiovascular disease, in: Kalimi, M. et Regelson, W., eds: Dehydroepiandrosterone (DHEA) Biochemical, Physiological and Clinical Aspects, Berlin, Walter de Gruyter, pp 191-213. Intracrinology 1999
128. El-Alfy, M., Luu-The, V., Huang, X.F., Berger, L., Labrie, F., Pelletier, G. (1999) Localization of type 5 17β-hydroxysteroid dehydrogenase, 3 β-hydroxysteroid dehydrogenase and androgen receptor in the human prostate by in situ hybridization and immunocytochemistry. Endocrinology, 140: 1481-1491. Intracrinology 1999
127. Labrie, F. (1999) Internal symposium: Editorial. Xth International Congress on Hormonal Steroids (Quebec City, Canada 17-21 June 1998). J. Steroid Biochem. Mol. Biol., 69: 1. Intracrinology 1999
126. Labrie, F., Simard, J., Pasqualini, J.R. (1999) Potential of DHEA as hormonal replacement therapy, 486 pages. Intracrinology 1999
125. Tremblay, A., Tremblay, G.B., Labrie, F., Giguère, V. (1999) Ligand-independent recruitment of SRC-1 to estrogen receptor Beta through phosphorylation of activation function AF-1. Mol. Cell., 3: 513-519. Intracrinology 1999
124. Tremblay, M.R., Luu-The, V., Leblanc, G., Noël, P., Breton, E., Labrie, F., Poirier, D. (1999) Spironolactone-related inhibitors of type II 17Beta-hydroxysteroid dehydrogenase: Chemical synthesis, receptor binding affinities, and proliferative/antiproliferative activities. Bioorg. Med. Chem., 7: 1013-1023. Intracrinology 1999
123. Zhu, D.-W., Campbell, R., Labrie, F., Lin, S.-X. (1999) Crystallization and preliminary crystal structure of the complex of 17Beta-hydroxysteroid dehydrogenase with a dual-site inhibitor. J. Steroid Biochem. Mol. Biol., 70: 229-235. Intracrinology 1999
122. Pelletier, G., Luu-The, V., Tetu, B., Labrie, F. (1999) Immunocytochemical localization of type 5 17beta-hydroxysteroid dehydrogenase in human reproductive tissues. J. Histochem Cytochem., 47: 731-738. Intracrinology 1999
121. Labrie, F. (2000) Prostate cancer and combined androgen blockade at all stages of disease, in: Khayat, D. et Hortobagyi, G.N., eds: Progress in Anti-Cancer Chemotherapy, France, Springer, pp 171-187. Intracrinology 2000
120. Labrie, F., Candas, B. (2000) Androgen blockade in prostate cancer [Letter-to-the-Editor]. Lancet, 356: 341-342. Intracrinology 2000
119. Labrie, F., Luu-The, V., Lin, S.-X., Simard, J., Labrie, C. (2000) Role of 17β-hydroxysteroid dehydrogenases in sex steroid formation in peripheral intracrine tissues. Trends Endocrinol. Metab., 11: 421-427. Intracrinology 2000
118. Labrie, F., Luu-The, V., Lin, S.-X., Simard, J., Labrie, C., El-Alfy, M., Pelletier, G., Bélanger, A. (2000) Intracrinology: role of the family of 17β-hydroxysteroid dehydrogenases in human physiology and disease. J. Mol. Endocrinol., 25: 1-16. Intracrinology 2000
117. Pelletier, G., Labrie, C., Labrie, F. (2000) Localization of oestrogen receptor alpha oestrogen receptor β and androgen receptors in the rat reproductive organs. J. Endocrinol., 165: 359-370. Intracrinology 2000
116. Prostate Cancer Triallist’ Collaborative Group; (2000) Maximum androgen blockade in advanced prostate cancer: an overvierw of the randomised trials. Lancet, 355: 1491-1498. Intracrinology 2000
115. Labrie, F., Luu-The, V., Labrie, C., Pelletier, G., El Alfy, M. (2000) Intracrinology and the skin. Horm. Res., 54: 218-229. Intracrinology 2000
114. Sourla, A., Richard, V., Labrie, F., Labrie, C. (2000) Exclusive androgenic effect of dehydroepiandrosterone in sebaceous glands of rat skin. J. Endocrinol., 166: 455-462. Intracrinology 2000
113. Couillard, S., Labrie, C., Gauthier, S., Mérand, Y., Singh, S.M., Candas, B., Labrie, F. (2000) Long-term inhibitory effect of the orally active and pure antiestrogen EM-800 on the growth of human breast cancer xenografts in nude mice. Int. J. Cancer, 85: 424-429. Intracrinology 2000
112. Labrie, C., Labrie, F., Bélanger, A., Simard, J., Luo, S., Martel, C. (2000) EM-652 (SCH 57068), a third generation SERM (selective estrogen receptor modulator), acting as pure antiestrogen in the mammary gland and endometrium, in: Coutinho, E.M. et Spinola, P., eds: Current Knowledge in Reproductive Medicine. Proceedings of the 10th World Congress on Human Reproduction, Salvador, Brazil, 4-8th May 1999, Elsevier Science B.V., pp 381-397. Intracrinology 2000
111. Labrie, F., Labrie, C., Bélanger, A., Simard, J., Luu-The, V., Candas, B. (2000) Mechanisms of action of estrogens and antiestrogens, in: Aso, T., Yanaihara, T. et Fujimoto, S., eds: The Menopause at the Millenium: Proceedings of the 9th World Congress on the Menopause, October 17-21, 1999, Yokohama, Japan, Parthenon Publishing, pp 14-22. Intracrinology 2000
110. Picard, F., Deshaies, Y., Lalonde, J., Samson, P., Labrie, C., Bélanger, A., Labrie, F., Richard, D. (2000) Effects of the estrogen antagonist EM-652.HCl on energy balance and lipid metabolism in ovariectomized rats. Int. J. Obes. Relat. Metab. Disord., 24: 830-840. Intracrinology 2000
109. Boivin, R.P., Luu-The, V., Lachance, R., Labrie, F., Poirier, D. (2000) Structure-activity relationships of 17alpha-derivatives of estradiol as inhibitors of steroid sulfatase. J. Med. Chem., 43: 4465-4478. Intracrinology 2000
108. Mauriège, P., Langin, D., Montminy, V., Martel, C., Després, J.P., Bélanger, A., Labrie, F., Deshaies, Y. (2000) Effect of a long-term percutaneous adrenal steroid treatment on rat adipose tissue metabolism. Int. J. Obes. Relat. Metab. Disord., 24: S148-S150. Intracrinology 2000
107. Labrie, F., Bélanger, A., Luu-The, V., Labrie, C., Simard, J., Lin, S.-X. (2000) DHEA, the precursor of androgens and estrogens in peripheral tissues in the human: intracrinology, in: Kalimi, M. et Regelson, W., eds: (DHEA): Biochemical Physiological and Clinical Aspects, pp 191-213. Intracrinology 2000
106. Sam, K.-M., Labrie, F., Poirier, D. (2000) N-Butyl-N-methyl-11-(3'-hydroxy-21', 17'-carbolactone-19'-nor-17'alpha-pregna-1',3', 5'(10')-trien-7'alpha-yl)-undecanamide: an inhibitor of type 2 17β-hydroxysteroid dehydrogenase that does not have oestrogenic or androgenic activity. Eur. J. Med. Chem., 35: 217-225. Intracrinology 2000
105. Singh, S.M., Gauthier, S., Labrie, F. (2000) Androgen receptor antagonists (antiandrogens): structure-activity relationships. Curr. Med. Chem., 7: 211-247. Intracrinology 2000
104. Labrie, F., Luu-The, V., Labrie, C., Simard, J. (2001) DHEA and its transformation into androgens and estrogens in peripheral target tissues: Intracrinology. Neuroendocrinologie, 22: 185-212. Intracrinology 2001
103. Pelletier, G., Luu-The, V., El Alfy, M., Li, S., Labrie, F. (2001) Immunoelectron microscopic localization of 3β-hydroxysteroid dehydrogenase and type 5 17β-hydroxysteroid dehydrogenase in the human prostate and mammary gland. J. Mol. Endocrinol., 26: 11-19. Intracrinology 2001
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