Fernand Labrie

Publications

Page 6 of 9, showing 50 records out of 402 total, starting on record 251, ending on 300

Publication Category Year
152. Bernier, F., Leblanc, G., Labrie, F., Luu-The, V. (1994) Structure of human estrogen and aryl sulfotransferase gene: Two mRNA species issued from a single gene. J. Biol. Chem., 269: 28200-28205. Intracrinology 1994
151. Bernier, F., Lopez, I., Labrie, F., Luu-The, V. (1994) Cloning and expression of cDNA encoding human placental estrogen sulfotransferase. Mol. Cell. Endocrinol., 99: R11-R15. Intracrinology 1994
150. Breton, R., Yang, F., Jin, J.Z., Li, B., Labrie, F., Lin, S.-X. (1994) Human 17?-hydroxysteroid dehydrogenase: overproduction using a baculovirus expression system and characterization. J. Steroid Biochem. Mol. Biol., 50: 275-282. Intracrinology 1994
149. Dionne, P., Singh, S.M., Labrie, F. (1994) 1H and 13C nuclear magnetic resonance assignments and stereochemistry of N-n-butyl-n-methyl-11-(16'?-chloro-3',17'? (and 17?)-dihydroxy-estra-1',4',5'(10')-trien-7?-yl) undecanamide. Steroids, 59: 493-497. Intracrinology 1994
148. Dupont, E., Simard, J., Luu-The, V., Labrie, F., Pelletier, G. (1994) Localization of 3?-hydroxysteroid dehydrogenase in rat brain as studied by in situ hybridization. Mol. Cell. Neurosci., 5: 119-123. Intracrinology 1994
147. Labrie, F., Simard, J., Luu-The, V., Pelletier, G. (1994) Molecular genetics, structure-function relationships and tissue-specific expression and tissue-specific expression and regulation of the 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase gene family, in: Bartke, A., ed. Function of Somatic Cells in the Testis, New York, NY, USA, Springer-Verlag, pp 126-150. Intracrinology 1994
146. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Belghmi, K., Bélanger, A. (1994) Structure, regulation and role of 3?-hydroxysteroid dehydrogenase, 17?-hydroxysteroid dehydrogenase and aromatase enzymes in formation of sex steroids in classical and peripheral intracrine tissues, in: Sheppard, M.C. et Stewart, P.M., eds: Hormones, Enzymes and Receptors, London, Baillière's clinical endocrinology and metabolism, pp 451-474. Intracrinology 1994
145. Li, X., Singh, S.M., Labrie, F. (1994) Highly efficient nucleophilic addition of alkyl Grignard reagents to 17-ketosteroids in the presence of cerium (III) chloride: synthesis of 17?-propyl-17?-hydroxy-4-androsten-3-one, an androgen receptor antagonist. Tetrahedron Lett., 35: 1157-1160. Intracrinology 1994
144. Martel, C., Gagné, D., Couet, J., Labrie, Y., Simard, J., Labrie, F. (1994) Rapid modulation of ovarian 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase gene expression by prolactin and human chorionic gonadotropin in the hypophysectomized rat. Mol. Cell. Endocrinol., 99: 63-71. Intracrinology 1994
143. Pelletier, G., Luu-The, V., Labrie, F. (1994) Immunocytochemical localization of 5?-reductase in rat brain. Mol. Cell. Neurosci., 5: 394-399. Intracrinology 1994
142. Rhéaume, E., Sanchez, R., Simard, J., Chang, Y.T., Wang, J., Pang, S., Labrie, F. (1994) Molecular basis of congenital adrenal hyperplasia in two sibs with classical nonsalt-losing 3?-hydroxysteroid dehydrogenase deficiency. J. Clin. Endocrinol. Metab., 79: 1012-1018. Intracrinology 1994
141. Sanchez, R., de Launoit, Y., Durocher, F., Bélanger, A., Labrie, F., Simard, J. (1994) Formation and degradation of dihydrotestosterone by recombinant members of the rat 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase (3?-HSD) family. Mol. Cell. Endocrinol., 103: 29-38. Intracrinology 1994
140. Sanchez, R., Mebarki, F., Rheaume, E., Laflamme, N., Forest, M.G., Bey-Omard, F., David, M., Morel, Y., Labrie, F., Simard, J. (1994) Functional characterization of the novel L108W and P186L mutations detected in the type II 3?-hydroxysteroid dehydrogenase gene of a male pseudohermaphrodite with congenital adrenal hyperplasia. Hum. Mol. Genet., 3: 1639-1645. Intracrinology 1994
139. Sanchez, R., Rhéaume, E., Laflamme, N., Rosenfield, R.L., Labrie, F., Simard, J. (1994) Detection and functional characterization of the novel missense mutation Y254D in type II 3?-hydroxysteroid dehydrogenase (3?-HSD) gene of a female patient with nonsalt-losing 3?-HSD deficiency. J. Clin. Endocrinol. Metab., 78: 561-567. Intracrinology 1994
138. Simard, J., Rhéaume, E., Leblanc, J.F., Wallis, S.C., Joplin, G.F., Gilbey, S., Allanson, J., Mettler, G., Bettendorf, M., Heinrich, U., Labrie, F. (1994) Congenital adrenal hyperplasia caused by a novel homozygous frameshift mutation 273DAA in type II 3?-hydroxysteroid dehydrogenase gene (HSD3?2) in three male patients of Afghan/Pakistani origin. Hum. Mol. Genet., 3: 327-330. Intracrinology 1994
137. Verreault, H., Dufort, I., Simard, J., Labrie, F., Luu-The, V. (1994) Dinucleotide repeat polymorphisms in the HSD3?2 gene. Hum. Mol. Genet., 3: 384. Intracrinology 1994
136. Zerah, M., Rhéaume, E., Mani, P., Schram, P., Simard, J., Labrie, F., New, M.I. (1994) No evidence of mutations in the genes for type I and type II 3?-hydroxysteroid dehydrogenase (3?-HSD) in nonclassical 3?-HSD deficiency. J. Clin. Endocrinol. Metab., 79: 1811-1817. Intracrinology 1994
135. Zhu, D.-W., Lee, X., Labrie, F., Lin, S.-X. (1994) Crystal growth of human estrogenic 17?-hydroxysteroid dehydrogenase. Acta Crystallogr., D50: 550-555. Intracrinology 1994
134. Labrie, F. (1993) Intracrinology: its impact on prostate cancer. Curr. Opin. Urol., 3: 381-387. Intracrinology 1993
133. Labrie, F. (1993) Mechanism of action and pure antiandrogenic properties of Flutamide. Cancer, 72: 3816-3827. Intracrinology 1993
132. Labrie, F. (1993) Non-steroidal antiandrogens, in: Droz, J.P., Cvitkovic, E., Armand, J.P. et Khoury, S., eds: Handook of Chemotherapy in Clinical Oncology, London, Scientific Communication International Ltd., pp 389-391. Intracrinology 1993
131. Labrie, F., Bélanger, A., Dupont, A., Luu-The, V., Simard, J., Labrie, C. (1993) Science behind total androgen blockade: from gene to combination therapy. Clin. Invest. Med., 16: 475-492. Intracrinology 1993
130. Labrie, F., Dupont, A., Simard, J., Luu-The, V., Bélanger, A. (1993) Intracrinology: the basis for the rational design of endocrine therapy at all stages of prostate cancer. Eur. Urol., 24 Suppl. 2: 94-105. Intracrinology 1993
129. Martel, C., Trudel, C., Couet, J., Labrie, C., Bélanger, A., Labrie, F. (1993) Blockade of androstenedione-induced stimulation of androgen-sensitive parameters in the rat prostate by combination of Flutamide and 4-MA. Mol. Cell. Endocrinol., 91: 43-49. Intracrinology 1993
128. Normand, T., Narod, S., Labrie, F., Simard, J. (1993) Detection of polymorphisms in the estradiol 17?-hydroxysteroid dehydrogenase II gene at the human EDH17B2 locus on 17q11-q21. Hum. Mol. Genet., 2: 479-483. Intracrinology 1993
127. Simard, J., Couet, J., Durocher, F., Labrie, Y., Sanchez, R., Breton, N., Turgeon, C., Labrie, F. (1993) Structure and tissue-specific expression of a novel member of the rat 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase (3?-HSD) family: the exclusive 3?-HSD gene expressed in the skin. J. Biol. Chem., 268: 19659-19668. Intracrinology 1993
126. Couture, P., Thériault, C., Simard, J., Labrie, F. (1993) Androgen receptor-mediated stimulation of 17?-hydroxysteroid dehydrogenase activity by dihydrotestosterone and medroxyprogesterone acetate in ZR-75-1 human breast cancer cells. Endocrinology, 132: 179-185. Intracrinology 1993
125. Li, S., Yan, X., Bélanger, A., Labrie, F. (1993) Prevention by dehydroepiandrosterone of the development of mammary carcinoma induced by 7,12-dimethylbenz(?)anthracene (DMBA) in the rat. Breast Cancer Res. Treat., 29: 203-217. Intracrinology 1993
124. Cusan, L., Dupont, A., Cossette, M., Labrie, F. (1993) Flutamide in the treatment of female androgenic alopecia. Can. J. Dermatol., 5: 421-427. Intracrinology 1993
123. de Launoit, Y., Simard, J., Zhao, H.F., Couture, P., Labrie, F. (1993) Structure-function relationships of multiple rat members of the 3?-hydroxysteroid dehydrogenase family (Chapter 14), in: Leung, P.C.K. et Hsueh, A.J.W., eds: Molecular Basis of Reproductive Endocrinology, New York, Springer-Verlag, pp 201-209. Intracrinology 1993
122. Dupont, E., Labrie, F., Luu-The, V., Pelletier, G. (1993) Ontogeny of 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase (3?-HSD) in rat testis as studied by immunocytochemistry. Anat. Embryol. (Berl.), 187: 583-589. Intracrinology 1993
121. Juneau, C., Dupont, E., Luu-The, V., Labrie, F., Pelletier, G. (1993) Ontogenesis of 3?-hydroxysteroid dehydrogenase ?5-?4 isomerase in the rat ovary as studied by immunocytochemistry and in situ hybridization. Biol. Reprod., 48: 226-234. Intracrinology 1993
120. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Labrie, C., Dupont, E., Martel, C., Couet, J., Trudel, C., Rhéaume, E., Breton, N., de Launoit, Y., Dumont, M., Zhao, H.F., Lachance, Y. (1993) Structure and control of expression of the 3?-HSD and 17?-HSD genes in classical steroidogenic and peripheral intracrine tissues, in: Leung, P.C.K., Hsueh, A.J.W. et Friesen, H.G., eds: Molecular Basis of Reproductive Endocrinology, New York, Karger, pp 112-143. Intracrinology 1993
119. Riley, S.C., Bassett, N.S., Berdusco, E.T., Yang, K., Leystra-Lantz, C., Luu-The, V., Labrie, F., Challis, J.R. (1993) Changes in the abundance of mRNA for type I 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase in the human placenta and fetal membranes during pregnancy and labor. Gynecol. Obstet. Invest., 35: 199-203. Intracrinology 1993
118. Simard, J., Rhéaume, E., Sanchez, R., de Launoit, Y., Laflamme, N., Luu-The, V., van Seters, A.P., Gordon, R.D., Heinrich, U., Moshang, T., New, M.I., Labrie, F. (1993) Molecular basis of congenital adrenal hyperplasia due to 3?-hydroxysteroid dehydrogenase deficiency. Mol. Endocrinol., 7: 716-728. Intracrinology 1993
117. Martel, C., Trudel, C., Couet, J., Labrie, C., Bélanger, A., Labrie, F. (1992) Blockade of androgen action by combined treatment with a pure antiandrogen (Flutamide) and a 5?-reductase inhibitor (4-MA), in: Giuliani, L. et Puppo, P., eds: Urology, Bologna, Monduzzi Editore, pp 605-610. Intracrinology 1992
116. Dumont, M., Luu-The, V., Dupont, E., Pelletier, G., Labrie, F. (1992) Characterization, expression and immunohistochemical localization of 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase in human skin. J. Invest. Dermatol., 99: 415-421. Intracrinology 1992
115. Labrie, C., Martel, C., Dufour, J.M., Lévesque, C., Mérand, Y., Labrie, F. (1992) Novel compounds inhibit estrogen formation and action. Cancer Res., 52: 610-615. Intracrinology 1992
114. Labrie, F., Simard, J., de Launoit, Y., Poulin, R., Thériault, C., Dumont, M., Dauvois, S., Martel, C., Li, S.; (1992) Androgens and breast cancer. Cancer Detect. Prev., 16: 31-38. Intracrinology 1992
113. Roy, R., Dauvois, S., Labrie, F., Bélanger, A. (1992) Estrogen-stimulated glucuronidation of dihydrotestosterone in MCF-7 human breast cancer cells. J. Steroid Biochem. Mol. Biol., 41: 579-582. Intracrinology 1992
112. Simard, J., de Launoit, Y., Haagensen, D.E., Labrie, F. (1992) Additive stimulatory action of glucocorticoids and androgens on basal and estrogen-repressed apolipoprotein D messenger RNA levels and secretion in human breast cancer cells. Endocrinology, 130: 1115-1121. Intracrinology 1992
111. Couet, J., Simard, J., Martel, C., Trudel, C., Labrie, Y., Labrie, F. (1992) Regulation of 3-ketosteroid reductase mRNA levels and 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase activity in rat liver by sex steroids and pituitary hormones. Endocrinology, 131: 3034-3044. Intracrinology 1992
110. de Launoit, Y., Simard, J., Durocher, F., Labrie, F. (1992) Androgenic 17?-hydroxysteroid dehydrogenase activity of expressed rat type I 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase. Endocrinology, 130: 553-555. Intracrinology 1992
109. de Launoit, Y., Zhao, H.F., Bélanger, A., Labrie, F., Simard, J. (1992) Expression of liver specific member of the 3?-hydroxysteroid dehydrogenase family, an isoform possessing an almost exclusive 3-keto steroid reductase activity. J. Biol. Chem., 267: 4513-4517. Intracrinology 1992
108. Dumont, M., Luu-The, V., de Launoit, Y., Labrie, F. (1992) Expression of human 17?-hydroxysteroid dehydrogenase in mammalian cells. J. Steroid Biochem. Mol. Biol., 41: 605-608. Intracrinology 1992
107. Dupont, E., Labrie, F., Luu-The, V., Pelletier, G. (1992) Immunocytochemical localization of 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase (3?-HSD) in human ovary. J. Clin. Endocrinol. Metab., 74: 994-998. Intracrinology 1992
106. Labrie, F., Simard, J., Luu-The, V., Bélanger, A., Pelletier, G. (1992) Structure, function and tissue-specific gene expression of 3?-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase enzymes in classical and peripheral intracrine steroidogenic tissues. J. Steroid Biochem. Mol. Biol., 43: 805-826. Intracrinology 1992
105. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Bélanger, A. (1992) Cloning, expression and regulation of tissue-specific expression of 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase in Cellular and Molecular Biology of the Adrenal Cortex, London, John Libbey Eurotext Ltd., pp 89-109. Intracrinology 1992
104. Labrie, F., Simard, J., Luu-The, V., Pelletier, G., Bélanger, A., Lachance, Y., Zhao, H.F., Labrie, C., Breton, N., de Launoit, Y., Dumont, M., Dupont, E., Rhéaume, E., Martel, C., Couet, J., Trudel, C. (1992) Structure and tissue-specific expression of 3?-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. J. Steroid Biochem. Mol. Biol., 41: 421-435. Intracrinology 1992
103. Labrie, F., Sugimoto, Y., Luu-The, V., Simard, J., Lachance, Y., Bachvarov, D., Leblanc, G., Durocher, F., Paquet, N. (1992) Structure of human type II 5?-reductase gene. Endocrinology, 131: 1571-1573. Intracrinology 1992
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