Fernand Labrie
Publications
Page 5 of 9, showing 50 records out of 402 total, starting on record 201, ending on 250
| Publication | Category | Year |
|---|---|---|
| 202. Poirier, D., Mérand, Y., Labrie, C., Labrie, F. (1996) D-Ring alkylamide derivatives of estradiol: Effect on ER-binding affinity and antiestrogenic activity. Bioorg. Med. Chem. Lett., 6: 2537-2542. | Intracrinology | 1996 |
| 201. Tchernof, A., Labrie, F., Bélanger, A., Després, J.P. (1996) Obesity and metabolic complications: contribution of DHEA and other steroid hormones. J. Endocrinol, 150: S155-S164. | Intracrinology | 1996 |
| 200. Chen, C., Bélanger, A., Labrie, F. (1996) Adrenal steroid precursors exert potent androgenic action in the hamster sebaceous glands of flank organs and ears. Endocrinology, 137: 1752-1757. | Intracrinology | 1996 |
| 199. Dufort, I., Tremblay, Y., Bélanger, A., Labrie, F., Luu-The, V. (1996) Isolation and characterization of a stereospecific 3β-hydroxysteroid sulfotransferase (pregnenolone sulfotransferase) cDNA. DNA Cell Biol., 15: 481-487. | Intracrinology | 1996 |
| 198. Labrie, F., Simard, J., Luu-The, V., Bélanger, A., Pelletier, G., Morel, Y., Mebarki, F., Sanchez, R., Durocher, F., Turgeon, C., Labrie, Y., Rhéaume, E., Labrie, C., Lachance, Y. (1996) The 3β hydroxysteroid dehydrogenase/isomerase gene family: lessons from type II 3β-HSD congenital deficiency, in: Proceeding 9th European Testis Workshop Signal Transduction in Testicular Cells - Basic and Clinical Aspects, Springer-Verlag, pp 185-218. | Intracrinology | 1996 |
| 197. Li, X., Singh, S.M., Luu-The, V., Côté, J., Laplante, S., Labrie, F. (1996) Vinyl fluoride as a mimic of the "intermediate" enol form in the 5?-reductase transformation: synthesis and in vitro activity of (N-1',1'-dimethylethyl)-3-haloandrost-3,5-diene-17?-carboxamides. Bioorg. Med. Chem., 4: 55-60. | Intracrinology | 1996 |
| 196. Lin, S.-X., Zhu, D.-W., Azzi, A., Campbell, R.L., Breton, R., Labrie, F., Ghosh, D., Pletnev, V., Duax, W.L., Pangborn, W. (1996) Studies on the 3D-structure of estrogenic 17β-hydroxysteroid dehydrogenase. J. Endocrinol., 150 Suppl.: S13-S20. | Intracrinology | 1996 |
| 195. Lopez-Solache, I., Luu-The, V., Séralini, G.E., Labrie, F. (1996) Heterogeneity of rat type I 5α-reductase cDNA: cloning, expression and regulation by pituitary implants and dihydrotestosterone. Biochim. Biophys. Acta, 1305: 139-144. | Intracrinology | 1996 |
| 194. Luu-The, V., Bernier, F., Dufort, I., Labrie, F. (1996) Molecular biology of steroid sulfotransferase. Ann. N.Y. Acad. Sci., 784: 137-148. | Intracrinology | 1996 |
| 193. Morissette, J., Durocher, F., Leblanc, J.-F., Normand, T., Labrie, F., Simard, J. (1996) Genetic linkage mapping of the human steroid 5α-reductase type 2 gene (SRD5?2) close to D2S352 on chromosome region 2p22-23. Cytogenet. Cell. Genet., 73: 304-307. | Intracrinology | 1996 |
| 192. Simard, J., Durocher, F., Mébarki, F., Turgeon, C., Sanchez, R., Labrie, Y., Couet, J., Trudel, C., Rhéaume, E., Morel, Y., Luu-The, V., Labrie, F. (1996) Molecular biology and genetics of the 3? hydroxysteroid dehydrogenase/?5??4 isomerase gene family. J. Endocrinol., 150 Suppl.: S189-S207. | Intracrinology | 1996 |
| 191. Simard, J., Rhéaume, E., Sanchez, R., Mebarki, F., Morel, Y., Zerah, M., New, M.I., Labrie, F. (1996) Relation between molecular defect and phenotypic manifestation of human 3β-hydroxysteroid dehydrogenase deficiency, in: New, M., ed. Frontiers Endocrinol., Serono Symposia Series, pp 39-68. | Intracrinology | 1996 |
| 190. Labrie, F., Bélanger, A., Simard, J., Luu-The, V., Labrie, C. (1995) Intracrinologie: autonomie et liberté des tissus périphériques. Ann. Endocrinol. (Paris), 56: 23-29. | Intracrinology | 1995 |
| 189. Labrie, F., Crawford, D.; (1995) Anti-androgens in treatment of prostate cancer. Lancet, 346: 1030-1031. | Intracrinology | 1995 |
| 188. Li, X., Singh, S.M., Côté, J., Laplante, S., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro evaluation of 4-substituted-N-(1,1-dimethylethyl)-3-oxo-4-androsten-17?-carboxamides as 5?-reductase inhibitors and antiendrogens. J. Med. Chem., 38: 1456-1461. | Intracrinology | 1995 |
| 187. Li, X., Singh, S.M., Labrie, F. (1995) Synthesis and in vitro activity of 17?-(N-alkyl)formamido/ alkylamido-4-aza-/4-methyl-4-aza-3-oxo-5?-androstan-3-ones as inhibitors of human 5?-reductase and antagonists on the androgen receptor. J. Med. Chem., 38: 1158-1173. | Intracrinology | 1995 |
| 186. Li, X., Singh, S.M., Lourdusamy, M., Mérand, Y., Veilleux, R., Labrie, F. (1995) Synthesis and in vitro antiandrogenic activity of 17?-hydroxy-17?-(w-hydroxy/haloalkyn-1'-yl)-4-methyl-4-aza-3-oxo-5?-androstan-(1-ene)-3-ones. Bioorg. Med. Chem. Lett., 5: 1061-1064. | Intracrinology | 1995 |
| 185. Sun, S., Narod, S., Aprikian, A., Ghadirian, P., Labrie, F. (1995) Androgen receptor and familial prostate cancer. Nature Medicine, 1: 848-849. | Intracrinology | 1995 |
| 184. Sugimoto, Y., Lopez-Solache, I., Labrie, F., Luu-The, V. (1995) Cations inhibit specifically Type I 5?-reductase found in human skin. J. Invest. Dermatol., 104: 775-778. | Intracrinology | 1995 |
| 183. Auger, S., Mérand, Y., Pelletier, J.D., Poirier, D., Labrie, F. (1995) Synthesis and biological activities of thioether derivatives related to the antiestrogens tamoxifen and ICI 164384. J. Steroid Biochem. Mol. Biol., 52: 547-565. | Intracrinology | 1995 |
| 182. Blais, Y., Sugimoto, K., Carrière, M.C., Haagensen, D.E., Labrie, F., Simard, J. (1995) Interleukin-6 inhibits the potent stimulatory action of androgens, glucocorticoids and interleukin-1 ? on apolipoprotein D and GCDFP-15 expression in human breast cancer cells. Int. J. Cancer, 62: 732-737. | Intracrinology | 1995 |
| 181. Labrie, F., Li, S., Labrie, C., Lévesque, C., Mérand, Y. (1995) Inhibitory effect of a steroidal antiestrogen (EM-170) on estrone-stimulated growth of 7,12-dimethylbenz(a)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 33: 237-244. | Intracrinology | 1995 |
| 180. Li, S., Lévesque, C., Geng, C.S., Yan, X., Labrie, F. (1995) Inhibitory effects of medroxyprogesterone acetate (MPA) and the pure antiestrogen EM-219 on estrone (E1)-stimulated growth of dimethylbenz(?)anthracene (DMBA)-induced mammary carcinoma in the rat. Breast Cancer Res. Treat., 34: 147-159. | Intracrinology | 1995 |
| 179. Dalla Valle, L., Couet, J., Labrie, Y., Simard, J., Belvedere, P., Simontacchi, C., Labrie, F., Colombo, L. (1995) Occurrence of cytochrome 450c17 mRNA and dehydroepiandrosterone biosynthesis in the rat gastrointestinal tract. Mol. Cell. Endocrinol., 111: 83-92. | Intracrinology | 1995 |
| 178. Labrie, F., Bélanger, A., Simard, J., Luu-The, V., Labrie, C. (1995) DHEA and peripheral androgen and estrogen formation: intracrinology. Ann. N.Y. Acad. Sci., 774: 16-28. | Intracrinology | 1995 |
| 177. Luu-The, V., Dufort, I., Paquet, N., Reimnitz, G., Labrie, F. (1995) Structural characterization and expression of the human dehydroepiandrosterone sulfotransferase gene. DNA Cell Biol., 14: 511-518. | Intracrinology | 1995 |
| 176. Doualla-Bell, F., Bonneau, M.J., Labrie, F., Fortier, M.A. (1995) Differential effects of a steroidal antiestrogen, EM-139, on prostaglandin and cAMP production in the circular and longitudinal layers of bovine myometrium. Biol. Reprod., 52: 1358-1363. | Intracrinology | 1995 |
| 175. Durocher, F., Morissette, J., Labrie, Y., Labrie, F., Simard, J. (1995) Mapping of the HSD17?2 gene encoding type II 17β-hydroxysteroid dehydrogenase close to D16S422 on chromosome 16q 24.1-q24.2. Genomics, 25: 724-726. | Intracrinology | 1995 |
| 174. Ghosh, D., Pletnev, V.Z., Zhu, D.-W., Wawrzak, Z., Duax, W.L., Pangborn, W., Labrie, F., Lin, S.-X. (1995) Structure of human estrogenic 17?-hydroxysteroid dehydrogenase at 2.20 a resolution. Structure, 3: 503-513. | Intracrinology | 1995 |
| 173. Guérin, S.L., Leclerc, S., Verreault, H., Labrie, F., Luu-The, V. (1995) Overlapping cis-acting elements located in the first intron of the gene for type I 3?-hydroxysteroid dehydrogenase modulate its transcriptional activity. Mol. Endocrinol., 9: 1583-1597. | Intracrinology | 1995 |
| 172. Labrie, Y., Durocher, F., Lachance, Y., Turgeon, C., Simard, J., Labrie, C., Labrie, F. (1995) The human type II 17?-hydroxysteroid dehydrogenase gene encodes two alternatively-spliced messenger RNA species. DNA Cell Biol., 14: 849-861. | Intracrinology | 1995 |
| 171. Li, X., Chen, C., Singh, S.M., Labrie, F. (1995) The enzyme and inhibitors of 4-ene-3-oxosteroid 5?-reductase. Steroids, 60: 430-441. | Intracrinology | 1995 |
| 170. Luu-The, V., Zhang, Y., Poirier, D., Labrie, F. (1995) Characteristics of human types 1, 2, and 3 17?-hydroxysteroid dehydrogenase activities: oxidation reduction and inhibition. J. Steroid Biochem. Mol. Biol., 55: 581-587. | Intracrinology | 1995 |
| 169. Mébarki, F., Sanchez, R., Rhéaume, E., Laflamme, N., Simard, J., Forest, M.G., Bey-Omar, F., David, M., Labrie, F., Morel, Y. (1995) Nonsalt-losing male pseudohermaphroditism due to the novel homozygous N100S mutation in the type II 3?-hydroxysteroid dehydrogenase (HSD3B2) gene. J. Clin. Endocrinol. Metab., 80: 2127-2134. | Intracrinology | 1995 |
| 168. Morissette, J., Rhéaume, E., Leblanc, J.-F., Luu-The, V., Labrie, F., Simard, J. (1995) Genetic linkage mapping of HSD3?1 and HSSD3?2 encoding human types I and II 3?-hydroxysteroid dehydrogenase/??????isomerase close to D1S514 and the centromeric D1Z5 locus. Cytogenet Cell Genet, 69: 59-62. | Intracrinology | 1995 |
| 167. Pelletier, G., Luu-The, V., Labrie, F. (1995) Immunocytochemical localization of type I 17?-hydroxysteroid dehydrogenase in the rat brain. Brain Res., 704: 233-239. | Intracrinology | 1995 |
| 166. Rhéaume, E., Sanchez, R., Mébarki, F., Gagnon, E., Carel, J.C., Chaussain, J.L., Morel, Y., Labrie, F., Simard, J. (1995) Identification and characterization of the G15D mutation found in a male patient with 3?-hydroxysteroid dehydrogenase (3?-HSD) deficiency: alteration of the putative NAD-binding domaine of type II 3?-HSD. Biochemistry, 34: 2893-2900. | Intracrinology | 1995 |
| 165. Simard, J., Rhéaume, E., Mébarki, F., Sanchez, R., New, M.I., Morel, Y., Labrie, F. (1995) Molecular basis of human 3?-hydroxysteroid dehydrogenase deficiency. J. Steroid Biochem. Mol. Biol., 53: 127-138. | Intracrinology | 1995 |
| 164. Simard, J., Sanchez, R., Durocher, F., Rhéaume, E., Turgeon, C., Labrie, Y., Luu-The, V., Mebarki, F., Morel, Y., de Launoit, Y., Labrie, F. (1995) Structure-function relationships and molecular genetics of the 3?-hydroxysteroid dehydrogenase gene family. J. Steroid Biochem. Mol. Biol., 55: 489-505. | Intracrinology | 1995 |
| 163. Zhu, D.-W., Zhou, M., Mao, Y., Labrie, F., Lin, S.-X. (1995) Crystallization of human estrogenic 17?-hydroxysteroid dehydrogenase under microgravity. J. Cryst. Growth, 156: 108-111. | Intracrinology | 1995 |
| 162. Bélanger, A., Candas, B., Dupont, A., Cusan, L., Diamond, P., Gomez, J.L., Labrie, F. (1994) Changes in serum concentration of conjugated and unconjugated steroids in 40- to 80-year old men. J. Clin. Endocrinol. Metab., 79: 1086-1090. | Intracrinology | 1994 |
| 161. Labrie, F. (1994) Intracrinology and Cancer Therapy. Science Watch, 5: 3-4. | Intracrinology | 1994 |
| 160. Labrie, F., Simard, J., Bélanger, A., Luu-The, V., Labrie, C. (1994) Molecular biology of the intracrine steroidogenic enzymes in the human prostate, in: Motta, M. et Serio, M., eds: Sex Hormones and Antihormones in Endocrine-Dependent Pathology: Basic and Clinical Aspects, New York, Elsevier, pp 77-92. | Intracrinology | 1994 |
| 159. Sugimoto, K., Simard, J., Veilleux, R., Haagensen, D.E., Labrie, F. (1994) Inverse relationships between cell proliferation and basal or androgen-stimulated apolipoprotein D secretion in LNCaP human prostate cancer cells. J. Steroid Biochem. Mol. Biol., 51: 167-174. | Intracrinology | 1994 |
| 158. Couet, J., Martel, C., Labrie, Y., Luo, S., Simard, J., Labrie, F. (1994) Opposite effects of prolactin and corticosterone on the expression and activity of 3?-hydroxysteroid dehydrogenase/?5-?4 isomerase in rat skin. J. Invest. Dermatol., 103: 60-64. | Intracrinology | 1994 |
| 157. Luu-The, V., Sugimoto, Y., Puy, L., Labrie, Y., Lopez Solache, I., Singh, M., Labrie, F. (1994) Characterization, expression and immunohistochemical localization of 5?-reductase in human skin. J. Invest. Dermatol., 102: 221-226. | Intracrinology | 1994 |
| 156. Pelletier, J.D., Labrie, F., Poirier, D. (1994) N-butyl, N-methyl, 11-3',17'?-dihydroxy-1'3'5'(10') estratrien-16'?-yl)-9-(R/S)bromo undecanamide: synthesis and 17?-HSD inhibiting activity, estrogenic activity and antiestrogenic activity. Steroids, 59: 536-547. | Intracrinology | 1994 |
| 155. Poirier, D., Auger, S., Mérand, Y., Simard, J., Labrie, F. (1994) Synthesis and antiestrogenic activity of diaryl thioether derivatives. J. Med. Chem., 37: 1115-1125. | Intracrinology | 1994 |
| 154. Labrie, Y., Couet, J., Simard, J., Labrie, F. (1994) Multihormonal regulation of dehydroepiandrosterone sulfotransferase mRNA levels in adult rat liver. Endocrinology, 134: 1693-1699. | Intracrinology | 1994 |
| 153. Young, J., Couzinet, B., Pholsena, M., Nahoul, K., Labrie, F., Schaison, G. (1994) Plasma 3?-hydroxy-?5-steroids in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. J. Clin. Endocrinol. Metab., 78: 299-304. | Intracrinology | 1994 |